What are the mechanisms that govern the formation of amyloid protein structures associated with human diseases such as Alzheimer’s disease, Parkinson’s disease, type 2 diabetes, Prion diseases and systemic amyloidosis? This is a question of fundamental biological importance, and the focus of the research in Dr. Wei-Feng Xue's lab.
Dr Wei-Feng Xue is Senior Lecturer in Chemical biology in the School of Biosciences. He received his PhD degree in Physical Chemistry on research regarding protein-protein/protein-ligand interactions in Prof. Sara Linse’s group at Lund University in Sweden (2006). He then went on to do postdoctoral research concerning the mechanism and the biological impact of amyloid assembly in Prof. Sheena Radford’s laboratory at the Astbury Centre for Structural Molecular Biology in the University of Leeds (2006-2011). His research interests include supramolecular protein assembly, protein folding and misfolding, amyloid and prions, and AFM imaging. As a member of the KFG, he contributes his expertise in amyloid and prion biophysics to the group, and conduct research projects on the fundamental mechanisms of prion growth, propagation and transmission using S. cerevisiae yeast prion models.
Interested in joining us as Postdoc, PhD student or Research Masters student on research projects on amyloid biochemistry, protein biophysics, or imaging of biological structures? Contact: W.F.Xue@kent.ac.uk