Epigenetics of repetitive DNA elements in the fission yeast Schizosaccharomyces pombe and the fungal pathogen Candida albicans
Dr Alessia Buscaino graduated in Molecular Biology at the University of Palermo (Italy) in 2000. In 2001, she was awarded an EMBL predoctoral fellowship and conducted her PhD research in the laboratory of Dr. Asifa Akhtar at the European Molecular Biology Laboratory (EMBL-Germany).
During her PhD, her interest in epigenetics and chromatin modifications flourished while investigating mechanisms of Dosage Compensation in Drosophila melanogaster.
Alessia has a long term interest in epigenetics and chromatin regulation.
She is particularly interested in studying the chromatin status associated with DNA repeats given that repeated DNA poses major challenges to genome stability. In many organisms, heterochromatin assembles over large blocks of repetitive DNA elements suppressing recombination and promoting genome stability. However, surprisingly, it is still unknown how repetitive DNA elements are targeted for heterochromatin formation. To investigate these questions Alessia was awarded an EMBO long-term post-doctoral fellowship to conduct research in the laboratory of Professor Robin Allshire (WTCCB-Edinburgh).During her post-doc she investigated how heterochromatin assembles on large blocks of DNA repeats in the fission yeast Schizosaccharomyces pombe. In 2013, she obtained a EMBO short-term Fellowship to investigate the chromatin status of Candida albicans repetitive DNA elements in Judith Berman laboratory (TAU University- Tel-Aviv, Israel).
Alessia joined the University of Kent and the Kent Fungal Group in July 2013 as a lecturer and group leader. Her group investigates the epigenetic mechanisms regulating the chromatin structure of large blocks of repeats using S. pombe and C. albicans as model systems.
Interested in joining us? Postdoc, PhD student and Master student applications always considered. Enquiries to: