• Jakhria T, Hellewell AL, Porter MY, Jackson MP, Tipping KW, Xue WF, Radford SE and Hewitt EW (2014) β2-microglobulin amyloid fibrils are nanoparticles that disrupt lysosomal membrane protein trafficking and inhibit protein degradation by lysosomes. Journal of Biological Chemistry 289: 35781-35794.

 

  • Goodchild SC, Sheynis T, Thompson R, Tipping KW, Xue WF, Ranson NA, Beales PA, Hewitt EW and Radford SE (2014) β2-Microglobulin amyloid fibril-induced membrane disruption is enhanced by endosomal lipids and acidic pH. PLoS One 9: e104492.

 

  • White SA, Buscaino A, Sanchez-Pulido L, Ponting CP, Nowicki MW, Allshire RC (2014)  The RFTS Domain of Raf2 Is Required for Cul4 Interaction and Heterochromatin Integrity in Fission Yeast. PLoS One 9(8):e104161.

 

  • Hess KC, Liu J, Manfredi G, Mühlschlegel FA, Buck J, Levin LR and Barrientos A (2014) A mitochondrial CO2-adenylyl cyclase-cAMP signalosome controls yeast normoxic cytochrome c oxidase activity. FASEB Journal 28: 4369-4380.

 

  • Johnson M, East DA and Mulvihill DP (2014) Formins determine the functional properties of actin filaments in yeast. Current Biology 24:1525-1530.

 

  • Lawrence AD, Frank S, Newnham S, Lee MJ, Brown IR, Xue WF, Rowe ML, Mulvihill DP, Prentice MB, Howard MJ and Warren MJ (2014) Solution structure of a bacterial microcompartment targeting peptide and its application in the construction of an ethanol bioreactor. ACS Synthetic Biology 3:454-465.

 

  • Marshall KE, Marchante R, Xue WF and Serpell LC (2014) The relationship between amyloid structure and cytotoxicity. Prion 8:28860.

 

  • Chu D, Thompson J and von der Haar T (2014) Charting the dynamics of translation. Biosystems 119:1-9.

 

  • Tuite MF, Howard MJ and Xue WF (2014) Dynamic prions revealed by magic. Chemical Biology 21:172-173.

 

  • Chu D, Kazana E, Bellanger N, Singh T, Tuite MF and von der Haar T (2014) Translation elongation can control translation initiation on eukaryotic mRNAs. EMBO Journal 33: 21-34.

 

  • Smethurst DG, Dawes IW and Gourlay CW (2014) Actin - a biosensor that determines cell fate in yeats

 

  • Ayer A, Gourlay CW and Dawes IW (2014) Cellular redox homeostasis, reactive oxygen species and replicating ageing in Saccharomyces cerevisiae

 

  • Talpaert MJ, Balfour A, Stevens S, Baker M, Muhlschlegel FA and Gourlay CW (2014) Candida biofilm formation on voice prostheses

 

  • Staniforth GL and Tuite MF (2014) Monoculture breeds poor social skills

 

  • Mead EJ, Masterton RJ, von der Haar T and Tuite MF (2014) Control and regulation of mRNA translation.

 

  • Tarrant D and von der Haar T (2014) Synonymous codons, ribosome speed, and eukaryotic gene expression regulation

 

  • Kazana E and von der Haar T (2014) The translational machinery is an optimized molecular network that affects cellular homeostasis and disease

 

  • Mulvihill DP (2014) Using fluorescence to study actomyosin in yeasts

 

  • Alic N, Tullet JM, Niccoli T, Broughton S, Hoddinott MP, Slack C, Gems D and Partridge L (2014) Cell-nonautonomous effects of dFOXO/DAF-16 in aging

 

  • Tullet JM, Araiz C, Sanders MJ, Au C, Benedetto A, Papatheodorou I, Clark E, Schmeisser K, Jones D, Schuster EF, Thornton JM and Gems D (2014) DAF-16/FoxO directly regulates an atypical AMP-activated protein kinase gamme isoform to mediate the effects of insulin/IGF-1 signaling on aging in Caenorhabditis elegans

 

  • Riesen M, Feyst I, Rattanavirotkul N, Ezcurra M, Tullet JM, Papatheodorou I, Ziehm M, Au C, Gilliat AF, Hellberg J, Thornton JM and Gems D (2014) MDL-1, a growth- and tumour-suppressor, slows aging and prevents germline hyperplasia and hypertrophy in C.elegans

2014 Publications

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